• Testosterone Propionate Pharm Tec

Description

Each ml of Testosterone Propionate contains Testosterone Propionate 100mg in oily base quantity sufficient.


Pharmacological classification

Androgenic Hormone.


Mechanism of action

Testosterone is secreted from Leydig cell of testes. It is responsible for development of secondary sex characters in males at the time of puberty and subsequent maintenance of spermatogenesis during reproductive life of males. It binds to intracellular receptors in target cells where as the hormone receptor complex translocates to nucleus where it attaches to specific binding sites on the chromosomes. This leads to increased synthesis of mRNA and protein.


Pharmacokinetic properties

Testosterone propionate is oil-based injectable testosterone. Testosterone Propionate is having anabolic as well as androgenic properties. The Propionate esters has shorter half life compared to cypionate & enanthate esters. Testosterone proprionate has a duration of effect of 1 to 2 days. Therefore Testosterone Propionate is much faster acting than othertestosterone esters such as cypionate orenanthate. Propionate is only a quickly effective testosterone that must be injected more often, and requires a much more frequent dosing schedule in order to maintain stable blood levels, Testosterone is 98% bound to a specific testosterone-estradiol binding globulin in plasma, and about 2% is free and about 90% of a dose of testosterone is excreated in the urine as glucuronic and sulphuric acid ie.,conjugates of testosterone and its metabolites, about 6% of a dose is excreated in the feaces, mostly in the conjugated form. Inactivation of testosterone occurs primarily in the liver. Testosterone is metabolized to various 17-keto steroids.


Indications

Male Testicular failure: hypogonadal disorders, eunuchiodism, endocrine impotence.hypopituitarism, loss of libido, delayed puberty, osteoporosis, infertility due to disorders of spermatogenesis, Male climacteric symptoms, hereditary angioneurotic oedema. Female Genitial carcinoma, Endometriosis, fibroids, breast carcinoma, menopausal syndrome.


Side effects and specical precautions

Testosterone Propionate, when administered in the body, is partially converted to both estrogen as well as Di-hydrotestosterone. These are often the cause of many side effects such as gynocomastia, water retention, hair loss and prostate enlargement. Also, as with most steroids, injected testosterone propionate will inhibit natural testosterone levels and HPTA (Hypothalamic Pituitary Testicular Axis). The advantage with testosterone propionate, in this respect, is that it will clear your system more quickly than other esters, and allow you to begin recovery more rapidly. If there is a predisposition and very high dosages are taken, the known androgenic-linked side effects such as acne vulgaris, accelerated hair loss, and increased growth of body hair and deep voice can occur. The toxic influence on the liver is minimal so that a liver damage is unlikely compared to enanthate esters. An increased libido is common both in men and women with the use of propionate. Testosterone propionate is a more painful injection, pronounced soreness and low-grade fever that may last for a few days, with swelling and noticeable pain around the injection site.


Contra-indications

Carcinoma of the male breast Carcinoma known or suspected of the prostate. Cardiac, hepatic or renal impairment. Hypercalcemia. Prepubertal males. Hypersensitivity to testosterone orany other excipients Pregnancy and feeding mothers as testosterone esters causes foetal harm.


Drug interactions

Anticoagulant Testosterone may potentiate the effects of anticoagulant. Antidiabetic agents & Insulin: may reduce the blood glucose level & insulin in diabetic patients. Oxyphenbutazon: concurrent administration of Oxyphenbutazone and androgens may result in elevated serum levels of oxyphenbutazon Rifampicin and Phenobarbitone may increase rate of metabolism.


Dosage and directions for use

Testosterone Propionate injections should be administered intramuscularly. The most common dosage is 50 to 10Omg, every day or 2nd day and total weekly dosage would be in the range of 300-400mg. Females: 50-100 mg three times in a weekf orthe treatment of breast cancer in women.


Preservation

Keep out of the reach and sight of children. Do not store above 30°C. Keep in the original package or container supplied. Do not use this product after the expiry date that is stated in the outer package. The expiry date refers to the last day of the month. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.


Presentation

5 ampoules are packed in a plastic tray. 2 such trays are packed in carton box. All pack sizes may not be marketed.

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Testosterone Propionate Pharm Tec

  • Prodavac: Pharm Tech
  • Tip: Testosterone Propionate Pharm Tec
  • Raspoloživost: Na lageru
  • 3.800,00Din


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